House - episode 9
Filed under: Medicine | 13 Comments »
On tonight’s episode of House, a famous jazz trumpeter who’s paralyzed from the waist down suffers sudden difficulty in breathing. He is rushed to the hospital where he is diagnosed with pneumonia in addition to his previous diagnosis of amyotrophic lateral sclerosis (better known as ALS or Lou Gehrig’s disease). House, of course, does not believe this is ALS. He settles on Wegener’s Granulomatosis (a disease primarily of the lungs and kidneys) as a culprit. When the musician develops an arm paralysis he believes it to be a stroke instead of a progression of the ALS (it’s his show, so he’s right, of course). Ultimately, the musician is found to have an arteriovenous malformation (AVM — an abnormal growth of blood vessels) pressing on the spine and causing his paralysis.
The show was a good character study and took a close look at Drs. House and Foreman, as well as Foreman’s previous physician supervisor. Foreman was offered a job in California and had to decide whether to stay with House or go west for higher pay and more perks (and less abuse).
While the character moments were good, the medicine was not particularly well done:
- ALS seems a reasonable diagnosis, given what was known of the musician’s history and symptoms.
- It would be quite a stretch for Wegener’s Granulomatosis to have affected both the lungs and spine without being detectable on an x-ray or CT scan.
- The AVM should have been visible on any previous blood vessel study (such as an MRA) despite being hidden by inflammation.
- There is only a very narrow window of time to give clot-busting drugs (such as tPA) after a stroke. The patient was well outside this window.
- House violates his own favorite Occam’s Law by deciding that the upper arm and lower extremity paralysis are caused by two separate diagnoses.
- Not only are the Young Gun doctors running labs and MRIs, but now they’re performing embolectomies by themselves — so apparently they’re trained interventional radiologists as well.



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