Black Adam #4: A Medical Review

cover, Black Adam #4Black Adam #4 “The Dark Age, part 4″
Peter Tomasi, writer
Doug Mahnke, penciler

Wounded by gunfire, Black Adam arrives in a veterinary clinic and demands that the doctor and her assistant treat his wounds. As part of his treatment, Adam required a blood transfusion, so both the doctor and her assistant donate their own blood.

Doctor: Relax. You’ve been out for over 2 hours.
Adam: Two hours?
Doctor: And I’d appreciate it if you waited till you left to pop open all my sutures, ’cause we’re all out of blood.
Adam: Whose blood?
Doctor: Luckily for you — and us — you’re an O positive. My assistant and I did what we needed to do.

There are two ways of interpreting what the doctor has said:

1. Black Adam and the doctor and her assistant are all O+. This is the only explanation that actually works, but I don’t think it’s what the author had in mind. First, it’s statistically unlikely. While O positive is the most common blood type, the chance for three random people to all have it is only 5%.1 Second, the conversation doesn’t really support this interpretation. The doctor specifically says Adam has O+, not “luckily we were all O+“.

OR

2. The doctor (and the author) have a misunderstanding of type O blood as it relates to transfusions. They are confusing “universal donor” with “universal recipient.” If this interpretation is correct, the doctor is making a couple of mistakes:
First, O negative is the universal donor, not O+. Second, Black Adam is receiving blood, not donating, and an entirely different set of rules apply. There is an inverse relationship between donating and receiving. Blood types that are good for donations are poor recipients, and vice versa. For instance, AB+ can only donate to other AB+, but they can receive blood from any blood type (they are the “universal recipient”); conversely, O-, the “universal donor”, can only receive other O- blood. When Black Adam develops a transfusion reaction, we’ll know why.

Warning: Science Content

For the purpose of discussing transfusions, there are two main components of blood: red blood cells and plasma.

Red blood cells are covered with special proteins2 that indicate blood type. People with type A blood have A proteins while those with type B have B proteins. Type AB has both A and B proteins on the surface, while type O has neither. These proteins are important because they are used by the body to detect cells which do not belong. If the wrong surface protein is detected, a transfusion reaction will occur. Type O blood cells can “slip under the radar” because they are missing both the A and B proteins. When donating blood, the red blood cells are the key component (modern blood transfusions use pRBC — packed Red Blood Cells — where only the red blood cells are transfused).

Plasma is the portion of the blood that contains the antibodies, specifically, antibodies against other blood cell proteins. People with type A blood will have Anti-B antibodies and will react against any cells with B protein. People with type B blood will have anti-A antibodies and react against any cells with A protein. People with type AB have neither anti-A or anti-B so will accept both A and B proteins. People with type O have both anti-A and anti-B and will react against A proteins and/or B proteins. When a patient is on the receiving end of a transfusion, their plasma is the key component to consider.3

To add one final wrinkle, if you read the comic, you’ll notice that Black Adam has received a whole blood transfusion (which is extremely rare in real world medicine. Usually only red blood cells are used). This means that not only are red blood cells transfused, but plasma as well. So not only do you have to worry about Adam’s plasma reacting with the donated red blood cells, but you also have to worry about the donated plasma reacting with Adam’s red blood cells. In this case, he should only receive a transfusion from an identical blood type — which in a roundabout way brings us back to the first answer.4

Other transfusionsOther Comic Book Transfusions

Notes:
1I’m going with the distribution of O+ in the US population (38%). Obviously, this wouldn’t apply to Black Adam, but I’ve yet to find any reliable data on the distribution of Quraci blood types, let alone Quraci blood types from a millennium ago — and 38% seems to be a good median value.
2Technically they’re glycoproteins (a structure composed of proteins and sugar molecules), not just proteins, but I’m trying to keep it as simple as possible (though that seems to be a moot point now. For more information, Wikipedia has quite a good explanation of blood types and transfusions).
3I have not mentioned the Rhesus factor (Rh, the positive or negative part of the blood type) yet because it is a little more confusing. Red-blood-cell-wise, it works in the same manner as the ABO blood types. People with a positive blood type have the Rh protein on the surface of their blood cells while those with negative blood type lack this protein. However, there is a slight difference when it comes to the plasma. Unlike the ABO blood types, people with Rh-negative blood will not generally develop anti-Rh antibodies unless they’ve been exposed to Rh-positive blood (generally from a previous transfusion or childbirth).
4None of this answers the key question of why a veterinarian has the proper supplies to type human blood.

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8 Responses to “ Black Adam #4: A Medical Review ”

  1. Well, that’ll teach him to go to a vet. :)

  2. haha, that dialogue was confusing me! Here I was thinking to myself “wait a minute, they can’t all be the same blood type!” and then I thought they were trying to do the universal doner kind of thing and I was like “that can’t be right, one’s O- and the other is AB+” so it was kind of confusing. My first thought, though was the whole “veterenarian has things to treat humans like that?”. hahaha, silly adam, vets vets are for rabbits!

  3. The vet regularly treats chimpanzees? Pan has the same blood types we do, IIRC.

  4. Thank you for the precision DR. House.
    What did you actually think of the issue?
    Best,
    Johnny.

  5. Questionable medicine aside, I find it to be a mediocre series. The return of Black Adam would have been a more powerful story had they waited longer for him to regain his powers, as it was, this is just a few months after he lost them in 52 (or was it World War III?)

    Black Adam has the potential to be an interesting character in that you don’t always know whether to root for him or against him. This story is touching on those points, but I’d like to see a little more.

  6. Thank you for this post. I read the House recap comments last week and was a little worried about the general populations perceptions of blood types.

    Was there no new episode of Private Practice this week?

  7. Cheryl,
    No new episode this week. Christmas specials were on instead.

  8. I know I’m a bit late to post this, I only found this website recently and have been reading older posts.

    I know the idea of having 3 random people have the same blood type seems far fetched, but back when I was still in school, I guy I started hanging out with, his girlfriend’s friend, and my girlfriend all shared my blood type (O+, the most common one apparently.)

    Keep in mind that just because something seems improbable statistically, it still happens, or else no one would ever win the lottery.

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